We often cut museum board in two capacities: for architectural models it is a great choice as the laser is very accurate and precise so the repetition will always be consistent and the pieces will fit together just as it was designed, keep in mind with museum board beyond 4-ply (about 1/16″) it is a good idea to start taking in to account the thickness of the actual material you will be using. and for frame mats for photos or art to sit inside the frame and look sharp. Window frames can be left in as a part of a facade or cut as a separate piece in order to give more depth to the model, depending on the thickness of the material these elements can be as thin as 1/64″, additional detail can also be added through scoring with lines or fill patterns, however it is important to note that scoring will add some degree of yellow/light brown discoloration to the surface as the residue from the material will settle on the surface with scoring rather than be pulled through the table as it does when the material is cut. The cut edge will usually be a dark brown with some degree of light scoring on the backside, this is often mitigated if necessary by either cutting a second piece for the opposite wall face or by painting the model when complete.
Frame mats are often laser cut as it allows for a more creative arrangement of the photos involved or a more free framing of the artwork rather than a shape restricted by the linear mat-cutter usually used in a frame store, or leaving the interior pieces as doors as in the case of a custom advent calendar 😀